Research articles in biosensing


Resolving altered base-pairing of RNA modifications with DNA nanoswitches.

IA Todkari, AR Chandrasekaran, JA Punnoose, S Mao, P Haruehanroengra, C Beckles, J Sheng & K Halvorsen
Nucleic Acids Research, 51: 11291 (2023). [PDF]

A non-enzymatic test for SARS-CoV-2 RNA using DNA nanoswitches.

J Vilcapoma, A Aliyeva, A Hayden, AR Chandrasekaran, L Zhou, JA Punnoose, D Yang, C Hansen, SCC Shiu, A Russell, K St. George, WP Wong & K Halvorsen
medRxiv, DOI: 2023.05.31.23290613 (2023). [PDF]

Fluorescent aptaswitch for detection of lead ions.

J Mathivanan, H Liu, J Gan, AR Chandrasekaran* & J Sheng*
ACS Applied Bio Materials, 5: 5089 (2022). [PDF]

A DNA-based smart reagent for detecting Alzheimer’s associated microRNAs.

AR Chandrasekaran & K Halvorsen
ACS Sensors, 6: 3176 (2021). [PDF]

DNA nanoswitch barcodes for multiplexed biomarker profiling.

AR Chandrasekaran,* M MacIsaac, J Vilcapoma, CH Hansen, D Yang, WP Wong* & K Halvorsen*
Nano Letters, 21: 469 (2021). [PDF]

Short DNA oligonucleotide as a Ag+ binding detector.

F Shen, S Mao, J Mathivanan, Y Wu, AR Chandrasekaran, H Liu, J Gan & J Sheng
ACS Omega, 5: 28565 (2020). [PDF]

Programmable low-cost DNA-based platform for viral RNA detection.

L Zhou, AR Chandrasekaran, JA Punnoose, G Bonenfant, S Charles, O Levchenko, P Badu, C Cavaliere, CT Pager & K Halvorsen
Science Advances, 6: eabc6246 (2020). [PDF]

Ribonuclease-responsive DNA nanoswitches.

AR Chandrasekaran,* R Trivedi & K Halvorsen*
Cell Reports Physical Sciences, 1: 100117 (2020). [PDF]

Parallel poly(A) homo- and hetero-duplex formation detection with an adapted DNA nanoswitch technique.

MAG Pickard, KB Brylow, LA Cisco, MR Anecelle, ML Pershun, AR Chandrasekaran, K Halvorsen & ML Gleghorn
RNA 26: 1118 (2020). [PDF]

A versatile biomolecular detection platform based on photo-induced enhanced Raman spectroscopy.

T Man, W Lai, M Xiao, X Wang, AR Chandrasekaran, H Pei & L Li
Biosensors and Bioelectronics, 147: 111742 (2019). [PDF]

A pH-operated triplex DNA device on molybdenum disulfide nanosheets.

W Ji, D Li, W Lai, X Yao, MF Alam, W Zhang, H Pei, L Li* & AR Chandrasekaran*
Langmuir, 35: 5050 (2019). [PDF]

Cellular microRNA detection with miRacles: microRNA activated conditional looping of engineered switches.

AR Chandrasekaran, M MacIsaac, P Dey, O Levchenko, L Zhou, M Andres, BK Dey & K Halvorsen
Science Advances, 5: eaau9443 (2019). [PDF]

Affinity-modulated molecular beacons on MoS2 nanosheets for microRNA detection.

M Xiao, AR Chandrasekaran, W Ji, F Li, T Man, C Zhu, X Shen, H Pei, Q Li & L Li
ACS Applied Materials and Interfaces, 10: 35794 (2018). [PDF]

Reconfigurable DNA nanoswitches for graphical readout of molecular signals.

AR Chandrasekaran*
ChemBioChem, 19: 1018 (2018). [PDF]

Shear dependent LC purification of an engineered  DNA nanoswitch and implications for DNA origami.

K Halvorsen, M Kizer, X Wang, AR Chandrasekaran & M Basanta-Sanchez
Analytical Chemistry, 89: 5673 (2017). [PDF]

Programmable DNA nanoswitches for detection of nucleic acid sequences.

AR Chandrasekaran, J Zavala & K Halvorsen
ACS Sensors, 1: 120 (2016). [PDF]