MAJOR UPDATES
We moved from a shared lab space into our own new lab space in the Life Sciences Research Building at UAlbany in April 2024!
Arun became an Adjunct Faculty in the Department of Biological Sciences at UAlbany.
Arun became an Affiliate Faculty in the Department of Nanoscale Science and Engineering at UAlbany.
People
We reached the highest number of people in the lab since we opened in June 2022. Earlier in 2024, we had 2 postdoctoral associates, 2 research associates, 2 PhD students, 4 undergraduate researchers and 2 high school researchers. Check out our team members here.
Hannah Talbot is the lab’s first PhD student. One of our lab’s undergraduate students, Hannah, started their PhD research in our lab in the Fall of 2024 through the Department of Biological Sciences at UAlbany.
Our postdoctoral associate Johnsi moved to an industry position at Curia Global.
Our research associate Arlin moved to an industry position at Eurofins.
Senior Postdoctoral Associate Madhan is promoted to Research Scientist beginning Jan 1, 2025.
CHANDRASEKARAN LAB IN THE MEDIA
We were highlighted in several media and news outlets for our work this year.
Our work on Switchback DNA was highlighted in UAlbany News and picked up by other news outlets.
UAlbany News: The shape of molecules to come: A Q&A on designing DNA nanostructures for biomedical applications
AzoNano: UAlbany researchers investigate unique properties of switchback DNA for nanotechnology innovations
American Society for Biochemistry and Molecular Biology: The shape of molecules to come
Phys.org: The shape of molecules to come: A Q&A on designing DNA nanostructures for biomedical applications
Newswise: The shape of molecules to come: A Q&A on designing DNA nanostructures for biomedical applications
Arun was ranked among the world’s top 2% researchers (along with 42 other UAlbany faculty), according to a Stanford University study published annually through Elsevier. This was highlighted in UAlbany News and Arun was interviewed at the Times Union newspaper.
UAlbany News: UAlbany researchers make top 2% worldwide list
Times Union article with Arun’s interview: Dozens of UAlbany researchers are ranked in top 2% worldwide
Peer-reviewed publications
Switchback RNA.
BR Madhanagopal, H Talbot, A Rodriguez & AR Chandrasekaran*
ACS Chemical Biology, 19: 2394 (2024).
The unusual structural properties and potential biological relevance of switchback DNA.
BR Madhanagopal, H Talbot, A Rodriguez, JM Louis, H Zeghal, S Vangaveti, K Reddy & AR Chandrasekaran*
Nature Communications, 15: 6636 (2024).
Differential electrophoretic mobility of synthetic DNA motifs and duplex DNA in various counter ions.
A Patel, L Punnoose & AR Chandrasekaran*
Chemical Communications, 60: 12706 (2024).
Barium concentration-dependent anomalous electrophoresis of synthetic DNA motifs.
BR Madhanagopal, A Rodriguez, M Cordones & AR Chandrasekaran*
ACS Applied Bio Materials, 7: 2704 (2024).
A DNA rotary nanodevice operated by enzyme-initiated strand resetting.
AR Chandrasekaran*
Chemical Communications, 60: 534 (2024).
preprints
Influence of metal ions on the isothermal self-assembly of DNA nanostructures.
A Rodriguez, BR Madhanagopal, K Sarkar, Z Nowzari, J Mathivanan, H Talbot, V Morya, K Halvorsen, S Vangaveti, JA Berglund & AR Chandrasekaran*
bioRxiv, 2024.11.04.621977 (2024).
Tuning the stability of DNA tetrahedra with base-stacking interactions.
JA Punnoose, D Cole, T Melfi, V Morya, BR Madhanagopal, AA Chen, SA Vangaveti, AR Chandrasekaran & K Halvorsen
bioRxiv, 2024.06.10.598265 (2024).
DNA nanotechnology in the undergraduate laboratory: Toehold-less strand displacement in switchback DNA.
BR Madhanagopal & AR Chandrasekaran*
ChemRxiv DOI: 10.26434/chemrxiv-2024-rv2tv (2024).
Cover features
Our work on switchback RNA and PX-JX2 device reconfiguration were featured on journal covers.
Awards
Madhan won The RNA Institute Travel Award to present his work at the Foundations of Nanoscience (FNANO) Annual Conference at Snowbird, Utah in April 2024.
Hannah won The RNA Institute Travel Award to present their work at the FNANO Annual Conference at Snowbird, Utah in April 2024.
Arun was awarded the Excellence in Research Award by The RNA Institute at the Annual RNA Institute Retreat at Lake George in June 2024.
Hannah won Best Poster Award at the Annual RNA Institute Retreat at Lake George in June 2024.
Madhan won Best Poster Award at the Life Sciences Research Symposium at UAlbany in November 2024.
Grants
Arun received an administrative supplement for equipment purchases from the NIGMS at NIH. We purchased a typhoon laser imager for the lab.
Arun received UAlbany’s Minerva Center Innovation Funding to undertake a research project with an undergraduate researcher.
Presentations
Lab members gave seminars, talks and poster presentations at various events in 2024.
Madhan Bharath Raj, Poster Presentation, Annual Biophysical Society Meeting, February 2024.
Madhan Bharath Raj, Poster Presentation, FNANO Annual Conference, April 2024.
Madhan Bharath Raj, Poster Presentation, Annual RNA Institute Retreat, June 2024.
Madhan Bharath Raj, Poster Presentation, 2nd NYC RNA Symposium, September 2024.
Madhan Bharath Raj, Poster Presentation, Annual Life Sciences Research Symposium, November 2024.
Jack Geary, Poster Presentation, Annual RNA symposium, October 2024.
Akul Patel, Poster Presentation, Annual RNA Institute Retreat, June 2024.
Akul Patel, Poster Presentation, Annual Life Sciences Research Symposium, November 2024.
Leah Punnoose, Poster Presentation, UAlbany Showcase Day, April 2024.
Leah Punnoose, Poster Presentation, Annual RNA Symposium, October 2024.
Leah Punnoose, Poster Presentation, Annual Life Sciences Research Symposium, November 2024.
Arlin Rodriguez, Poster Presentation, Annual Biophysical Society Meeting, February 2024.
Arlin Rodriguez, Poster Presentation, FNANO Annual Conference, April 2024.
Aleena Saleem, Poster Presentation, Annual Life Sciences Research Symposium, November 2024.
Hannah Talbot, Poster Presentation, Annual Biophysical Society Meeting, February 2024.
Hannah Talbot, Flash Talk, Annual Biophysical Society Meeting, February 2024.
Hannah Talbot, Oral Presentation, FNANO Annual Conference, April 2024.
Hannah Talbot, Poster Presentation, Annual RNA Institute Retreat, June 2024.
Hannah Talbot, Poster Presentation, Annual RNA Symposium, October 2024.
Hannah Talbot, Poster Presentation, Annual Life Sciences Research Symposium, November 2024.
Arun Richard Chandrasekaran, Oral presentation, Annual Biophysical Society Meeting, February 2024.
Arun Richard Chandrasekaran, Oral presentation, Annual RNA Institute Retreat, June 2024.
Arun Richard Chandrasekaran, Invited presentation, The RNA Institute Executive Board Meeting, June 2024.
Arun Richard Chandrasekaran, Invited seminar, Department of Nanoscale Science and Engineering, UAlbany, September 2024.
Arun Richard Chandrasekaran, Invited seminar, University of Nebraska Medical Center, October 2024.
Arun Richard Chandrasekaran, Invited seminar, Northeast Regional Laboratory Staff & Core Directors Meeting, October 2024.